Version 5.4
Mus musculus Gene: Dpp9
Summary
InnateDB Gene IDBG-191834.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Dpp9
Gene Name dipeptidylpeptidase 9
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000001229
Encoded Proteins
IDBP-191836
dipeptidylpeptidase 9
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000142002:
This gene encodes a protein that is a member of the S9B family in clan SC of the serine proteases. The protein has been shown to have post-proline dipeptidyl aminopeptidase activity, cleaving Xaa-Pro dipeptides from the N-termini of proteins. Although the activity of this protein is similar to that of dipeptidyl peptidase 4 (DPP4), it does not appear to be membrane bound. In general, dipeptidyl peptidases appear to be involved in the regulation of the activity of their substrates and have been linked to a variety of diseases including type 2 diabetes, obesity and cancer. Several transcript variants of this gene have been described but not fully characterized. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:56186682-56218889
Strand Reverse strand
Band D
Transcripts
ENSMUST00000038794 ENSMUSP00000046604
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004177 aminopeptidase activity
GO:0008236 serine-type peptidase activity
GO:0042802 identical protein binding
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000142002
View Gene Order
ENSBTAG00000021134
Not yet available
Cross-References
SwissProt Q8BVG4
TrEMBL
UniProt Splice Variant
Entrez Gene 224897
UniGene Mm.407924
RefSeq NM_172624 XM_006524154 XM_006524155
OMIM
CCDS CCDS37663
HPRD
IMGT
MGI ID MGI:2443967
MGI Symbol Dpp9
EMBL AK050021 AK078301 AK131178 BC057631
GenPept AAH57631 BAC34034 BAC37211 BAD21428
RNA Seq Atlas 224897

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca