Version 5.4
Mus musculus Gene: Pex16
Summary
InnateDB Gene IDBG-192208.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pex16
Gene Name peroxisomal biogenesis factor 16
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000027222
Encoded Proteins
IDBP-192210
peroxisomal biogenesis factor 16
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000121680:
The protein encoded by this gene is an integral peroxisomal membrane protein. An inactivating nonsense mutation localized to this gene was observed in a patient with Zellweger syndrome of the complementation group CGD/CG9. Expression of this gene product morphologically and biochemically restores the formation of new peroxisomes, suggesting a role in peroxisome organization and biogenesis. Alternative splicing has been observed for this gene and two variants have been described. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:92374676-92381217
Strand Forward strand
Band E1
Transcripts
ENSMUST00000028650 ENSMUSP00000028650
ENSMUST00000155891
ENSMUST00000154669
ENSMUST00000148386
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008022 protein C-terminus binding
Biological Process
GO:0006625 protein targeting to peroxisome
GO:0007031 peroxisome organization
GO:0016557 peroxisome membrane biogenesis
GO:0016558 protein import into peroxisome matrix
GO:0022615 protein to membrane docking
GO:0032581 ER-dependent peroxisome organization
GO:0045046 protein import into peroxisome membrane
GO:0070972 protein localization to endoplasmic reticulum
Cellular Component
GO:0005777 peroxisome
GO:0005778 peroxisomal membrane
GO:0005779 integral component of peroxisomal membrane
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000121680
View Gene Order
ENSBTAG00000003126
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu04146
Peroxisome pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa04146
Peroxisome pathway
INOH
PID NCI
Cross-References
SwissProt Q91XC9
TrEMBL
UniProt Splice Variant
Entrez Gene 18633
UniGene
RefSeq NM_145122
OMIM
CCDS CCDS16444
HPRD
IMGT
MGI ID MGI:1338829
MGI Symbol Pex16
EMBL AK143073 AL731709 BC010822 CH466519
GenPept AAH10822 BAE25262 CAM20621 EDL27597
RNA Seq Atlas 18633

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca