InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Pex16

Summary

InnateDB Protein

IDBP-192210.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Pex16

Protein Name

peroxisomal biogenesis factor 16

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000028650

InnateDB Gene

IDBG-192208 (Pex16)

Protein Structure

UniProt Annotation

Function

Required for peroxisome membrane biogenesis. May play a role in early stages of peroxisome assembly. Can recruit other peroxisomal proteins, such as PEX3 and PMP34, to de novo peroxisomes derived from the endoplasmic reticulum (ER). May function as receptor for PEX3 (By similarity). {ECO:0000250}.

Subcellular Localization

Peroxisome membrane {ECO:0000250}; Multi- pass membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.

Predicted by orthology
Total	5 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0008022	protein C-terminus binding

Biological Process

GO:0006625	protein targeting to peroxisome
GO:0007031	peroxisome organization
GO:0016557	peroxisome membrane biogenesis
GO:0016558	protein import into peroxisome matrix
GO:0022615	protein to membrane docking
GO:0032581	ER-dependent peroxisome organization
GO:0045046	protein import into peroxisome membrane
GO:0070972	protein localization to endoplasmic reticulum

Cellular Component

GO:0005777	peroxisome
GO:0005778	peroxisomal membrane
GO:0005779	integral component of peroxisomal membrane
GO:0005783	endoplasmic reticulum
GO:0005789	endoplasmic reticulum membrane
GO:0016020	membrane