Mus musculus Gene: Ndst4
Summary
InnateDB Gene IDBG-192456.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ndst4
Gene Name N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
Synonyms 4930439H17Rik
Species Mus musculus
Ensembl Gene ENSMUSG00000027971
Encoded Proteins
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000138653:
Gene Information
Type Protein coding
Genomic Location Chromosome 3:125404094-125724986
Strand Forward strand
Band G1
Transcripts
ENSMUST00000147016
ENSMUST00000144344 ENSMUSP00000120687
ENSMUST00000173932 ENSMUSP00000133341
ENSMUST00000174648 ENSMUSP00000133575
ENSMUST00000172632
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008146 sulfotransferase activity
GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity
GO:0016787 hydrolase activity
GO:0019213 deacetylase activity
Biological Process
GO:0008152 metabolic process
GO:0015012 heparan sulfate proteoglycan biosynthetic process
GO:0030210 heparin biosynthetic process
Cellular Component
GO:0000139 Golgi membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
KEGG
Glycosaminoglycan biosynthesis pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
HS-GAG biosynthesis pathway
Mucopolysaccharidoses pathway
Myoclonic epilepsy of Lafora pathway
Defective B4GALT7 causes EDS, progeroid type pathway
Defective CHST6 causes MCDC1 pathway
MPS VI - Maroteaux-Lamy syndrome pathway
Defective PAPSS2 causes SEMD-PA pathway
Metabolism of carbohydrates pathway
MPS IIID - Sanfilippo syndrome D pathway
Defective SLC26A2 causes chondrodysplasias pathway
MPS IX - Natowicz syndrome pathway
Defective EXT1 causes exostoses 1, TRPS2 and CHDS pathway
Defective CHST14 causes EDS, musculocontractural type pathway
Heparan sulfate/heparin (HS-GAG) metabolism pathway
MPS IV - Morquio syndrome B pathway
Defective B3GAT3 causes JDSSDHD pathway
Defective CHST3 causes SEDCJD pathway
MPS IV - Morquio syndrome A pathway
Defective EXT2 causes exostoses 2 pathway
Diseases associated with glycosaminoglycan metabolism pathway
MPS II - Hunter syndrome pathway
Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) pathway
Glycosaminoglycan metabolism pathway
Diseases of glycosylation pathway
MPS VII - Sly syndrome pathway
Defective CHSY1 causes TPBS pathway
Metabolism pathway
MPS I - Hurler syndrome pathway
MPS IIIA - Sanfilippo syndrome A pathway
MPS IIIC - Sanfilippo syndrome C pathway
Disease pathway
Glycogen storage diseases pathway
MPS IIIB - Sanfilippo syndrome B pathway
KEGG
Glycosaminoglycan biosynthesis pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL D3YWZ6
UniProt Splice Variant
Entrez Gene 64580
UniGene Mm.444289
RefSeq NM_022565 XM_006501859
OMIM
CCDS CCDS17820
HPRD
IMGT
MGI ID MGI:1932545
MGI Symbol Ndst4
EMBL AC111141 AC140797 AC164153
GenPept
RNA Seq Atlas 64580