Version 5.4
Mus musculus Gene: Cd82
Summary
InnateDB Gene IDBG-192552.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cd82
Gene Name CD82 antigen
Synonyms AA682076; AL023070; C33; IA4; Kai1; Tspan27
Species Mus musculus
Ensembl Gene ENSMUSG00000027215
Encoded Proteins
IDBP-192554
CD82 antigen
IDBP-192556
CD82 antigen
IDBP-258510
CD82 antigen
IDBP-258512
CD82 antigen
IDBP-274081
CD82 antigen
IDBP-532642
CD82 antigen
IDBP-539608
CD82 antigen
IDBP-539863
CD82 antigen
IDBP-541172
CD82 antigen
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000085117:
This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. Its expression and that of p53 are strongly correlated, and the loss of expression of these two proteins is associated with poor survival for prostate cancer patients. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:93419111-93463140
Strand Reverse strand
Band E1
Transcripts
ENSMUST00000099696 ENSMUSP00000097287
ENSMUST00000028644 ENSMUSP00000028644
ENSMUST00000111257 ENSMUSP00000106888
ENSMUST00000111256 ENSMUSP00000106887
ENSMUST00000116457 ENSMUSP00000112158
ENSMUST00000126772
ENSMUST00000123565 ENSMUSP00000114762
ENSMUST00000150508 ENSMUSP00000120183
ENSMUST00000145553 ENSMUSP00000115310
ENSMUST00000144168
ENSMUST00000124804 ENSMUSP00000115349
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 21 interaction(s) predicted by orthology.
Predicted by orthology
Total 21 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
GO:0016021 integral component of membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000085117
View Gene Order
ENSBTAG00000031252
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu04115
p53 signaling pathway pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_11
TCR pathway
REACTOME
KEGG
hsa04115
p53 signaling pathway pathway
INOH
PID NCI
era_genomic_pathway
Validated nuclear estrogen receptor alpha network
p53downstreampathway
Direct p53 effectors
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.406342 Mm.4261
RefSeq NM_001136055 NM_001271430 NM_001271431 NM_001271432 NM_001271461 NM_001271462 NM_007656 XM_006498652
OMIM
CCDS CCDS16454
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca