Version 5.4
Mus musculus Gene: Nrtn
Summary
InnateDB Gene IDBG-192865.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Nrtn
Gene Name neurturin
Synonyms NTN
Species Mus musculus
Ensembl Gene ENSMUSG00000039481
Encoded Proteins
IDBP-192867
neurturin
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000171119:
Neurturin is a member of the TGF-beta subfamily, TRN. This gene signals through RET and a GPI-linked coreceptor, and promotes survival of neuronal populations. A neurturin mutation has been described in a family with Hirschsprung Disease. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:56751325-56757530
Strand Reverse strand
Band D
Transcripts
ENSMUST00000044752 ENSMUSP00000046512
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008083 growth factor activity
Biological Process
GO:0001755 neural crest cell migration
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
GO:0021675 nerve development
GO:0031175 neuron projection development
Cellular Component
GO:0005576 extracellular region
GO:0030424 axon
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000171119
View Gene Order
ENSBTAG00000000413
Not yet available
Pathways
NETPATH
REACTOME
REACT_236183
NCAM1 interactions pathway
REACT_261444
Axon guidance pathway
REACT_188576
Developmental Biology pathway
REACT_237796
NCAM signaling for neurite out-growth pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_18312
NCAM1 interactions pathway
REACT_18334
NCAM signaling for neurite out-growth pathway
REACT_111045
Developmental Biology pathway
REACT_18266
Axon guidance pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.480863 Mm.8074
RefSeq NM_008738 XM_006523801
OMIM
CCDS CCDS28913
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca