Version 5.4
Mus musculus Gene: Gtf2f1
Summary
InnateDB Gene IDBG-193303.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gtf2f1
Gene Name general transcription factor IIF, polypeptide 1
Synonyms 2810405L04Rik; C76800; RAP74
Species Mus musculus
Ensembl Gene ENSMUSG00000002658
Encoded Proteins
IDBP-193307
general transcription factor IIF, polypeptide 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000125651:
Gene Information
Type Protein coding
Genomic Location Chromosome 17:57003405-57011288
Strand Reverse strand
Band D
Transcripts
ENSMUST00000002733 ENSMUSP00000002733
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 57 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 57 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003824 catalytic activity
GO:0005515 protein binding
GO:0008134 transcription factor binding
GO:0019211 phosphatase activator activity
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006367 transcription initiation from RNA polymerase II promoter
GO:0009615 response to virus
GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter
GO:0043085 positive regulation of catalytic activity
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
Cellular Component
GO:0005634 nucleus
GO:0030054 cell junction
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000125651
View Gene Order
ENSBTAG00000021016
Not yet available
Pathways
NETPATH
REACTOME
REACT_230204
RNA Polymerase II Transcription Initiation And Promoter Clearance pathway
REACT_203462
Formation of the Early Elongation Complex pathway
REACT_249110
mRNA Splicing pathway
REACT_244380
RNA Polymerase II Transcription Initiation pathway
REACT_235610
mRNA Splicing - Minor Pathway pathway
REACT_255334
RNA Polymerase II Promoter Escape pathway
REACT_226759
Formation of RNA Pol II elongation complex pathway
REACT_232708
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening pathway
REACT_226490
RNA Polymerase II Transcription Elongation pathway
REACT_255009
RNA Polymerase II Pre-transcription Events pathway
REACT_258231
mRNA Capping pathway
REACT_233572
Gene Expression pathway
REACT_260226
mRNA Splicing - Major Pathway pathway
REACT_233950
Processing of Capped Intron-Containing Pre-mRNA pathway
REACT_242255
RNA Polymerase II Transcription pathway
REACT_257596
RNA Pol II CTD phosphorylation and interaction with CE pathway
KEGG
mmu03022
Basal transcription factors pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_2
AndrogenReceptor pathway
REACTOME
REACT_6344
Tat-mediated HIV elongation arrest and recovery pathway
REACT_6143
Pausing and recovery of Tat-mediated HIV elongation pathway
REACT_6354
Viral Messenger RNA Synthesis pathway
REACT_467
mRNA Splicing - Major Pathway pathway
REACT_1753
mRNA Splicing - Minor Pathway pathway
REACT_125
Processing of Capped Intron-Containing Pre-mRNA pathway
REACT_1470
mRNA Capping pathway
REACT_1655
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening pathway
REACT_22107
RNA Polymerase II Pre-transcription Events pathway
REACT_1845
Formation of RNA Pol II elongation complex pathway
REACT_846
Formation of the Early Elongation Complex pathway
REACT_833
RNA Polymerase II Transcription Elongation pathway
REACT_2089
RNA Polymerase II Promoter Escape pathway
REACT_1851
RNA Polymerase II Transcription Initiation pathway
REACT_834
RNA Polymerase II Transcription Initiation And Promoter Clearance pathway
REACT_975
RNA Pol II CTD phosphorylation and interaction with CE pathway
REACT_22201
Formation of HIV elongation complex in the absence of HIV Tat pathway
REACT_6332
HIV Transcription Initiation pathway
REACT_6244
Pausing and recovery of HIV elongation pathway
REACT_6253
RNA Polymerase II HIV Promoter Escape pathway
REACT_6319
Formation of the HIV-1 Early Elongation Complex pathway
REACT_6346
Formation of HIV-1 elongation complex containing HIV-1 Tat pathway
REACT_6162
Tat-mediated elongation of the HIV-1 transcript pathway
REACT_6261
Abortive elongation of HIV-1 transcript in the absence of Tat pathway
REACT_6237
RNA Pol II CTD phosphorylation and interaction with CE pathway
REACT_6259
HIV elongation arrest and recovery pathway
REACT_6233
Transcription of the HIV genome pathway
REACT_6361
Late Phase of HIV Life Cycle pathway
REACT_6167
Influenza Infection pathway
REACT_6152
Influenza Viral RNA Transcription and Replication pathway
REACT_6274
HIV Transcription Elongation pathway
REACT_1366
RNA Polymerase II Transcription pathway
REACT_6256
HIV Life Cycle pathway
REACT_6185
HIV Infection pathway
REACT_6145
Influenza Life Cycle pathway
REACT_1735
mRNA Splicing pathway
REACT_71
Gene Expression pathway
REACT_116125
Disease pathway
REACT_209718
RNA Polymerase II Transcription pathway
REACT_207332
mRNA Capping pathway
REACT_205948
mRNA Splicing - Major Pathway pathway
REACT_206725
mRNA Splicing pathway
REACT_205499
RNA Polymerase II Pre-transcription Events pathway
REACT_202835
RNA Polymerase II Promoter Escape pathway
REACT_226022
Gene Expression pathway
REACT_226302
Processing of Capped Intron-Containing Pre-mRNA pathway
REACT_218933
RNA Polymerase II Transcription Elongation pathway
REACT_206737
Formation of RNA Pol II elongation complex pathway
REACT_207660
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening pathway
REACT_217207
mRNA Splicing - Minor Pathway pathway
REACT_220130
RNA Pol II CTD phosphorylation and interaction with CE pathway
REACT_208384
RNA Polymerase II Transcription Initiation And Promoter Clearance pathway
REACT_207656
RNA Polymerase II Transcription Initiation pathway
REACT_205514
Formation of the Early Elongation Complex pathway
KEGG
hsa03022
Basal transcription factors pathway
INOH
PID NCI
Cross-References
SwissProt Q3THK3
TrEMBL
UniProt Splice Variant
Entrez Gene 98053
UniGene Mm.24632
RefSeq NM_133801 XM_006525194
OMIM
CCDS CCDS37667
HPRD
IMGT
MGI ID MGI:1923848
MGI Symbol Gtf2f1
EMBL AK168236 AK168243 BC023081 BC031123 CH466537
GenPept AAH23081 AAH31123 BAE40186 BAE40193 EDL38221
RNA Seq Atlas 98053

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca