InnateDB Protein
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IDBP-193307.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Gtf2f1
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Protein Name
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general transcription factor IIF, polypeptide 1
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Synonyms
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2810405L04Rik; C76800; RAP74;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000002733
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InnateDB Gene
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IDBG-193303 (Gtf2f1)
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Protein Structure
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Function |
TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation (By similarity). {ECO:0000250}.
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Subcellular Localization |
Nucleus {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 57 interaction(s) predicted by orthology.
Experimentally validated |
Total |
3
[view]
|
Protein-Protein |
3
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
57 [view]
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Molecular Function |
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Biological Process |
GO:0006367
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transcription initiation from RNA polymerase II promoter
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GO:0009615
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response to virus
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GO:0032968
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positive regulation of transcription elongation from RNA polymerase II promoter
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GO:0043085
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positive regulation of catalytic activity
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GO:0045944
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positive regulation of transcription from RNA polymerase II promoter
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Cellular Component |
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PDB ID |
MGI:1923848
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InterPro |
IPR008851
Transcription initiation factor IIF, alpha subunit
IPR011039
Transcription Factor IIF, Rap30/Rap74, interaction
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PFAM |
PF05793
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q3THK3
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PhosphoSite |
PhosphoSite-Q3THK3
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
98053
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UniGene |
Mm.24632
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RefSeq |
NP_598562
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MGI ID |
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MGI Symbol |
Gtf2f1
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OMIM |
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CCDS |
CCDS37667
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HPRD |
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IMGT |
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EMBL |
AK168236
AK168243
BC023081
BC031123
CH466537
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GenPept |
AAH23081
AAH31123
BAE40186
BAE40193
EDL38221
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