InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Cabp1

Summary

InnateDB Gene

IDBG-193413.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Cabp1

Gene Name

calcium binding protein 1

Synonyms

caldendrin

Species

Mus musculus

Ensembl Gene

ENSMUSG00000029544

Encoded Proteins

IDBP-193415

calcium binding protein 1

IDBP-256683

calcium binding protein 1

IDBP-256685

calcium binding protein 1

IDBP-256687

calcium binding protein 1

IDBP-789844

calcium binding protein 1

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000157782:
Calcium binding proteins are an important component of calcium mediated cellular signal transduction. This gene encodes a protein that belongs to a subfamily of calcium binding proteins which share similarity to calmodulin. The protein encoded by this gene regulates the gating of voltage-gated calcium ion channels. This protein inhibits calcium-dependent inactivation and supports calcium-dependent facilitation of ion channels containing voltage-dependent L-type calcium channel subunit alpha-1C. This protein also regulates calcium-dependent activity of inositol 1,4,5-triphosphate receptors, P/Q-type voltage-gated calcium channels, and transient receptor potential channel TRPC5. This gene is predominantly expressed in retina and brain. Alternative splicing results in multiple transcript variants encoding disinct isoforms. [provided by RefSeq, Jul 2012]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 5:115168689-115194381

Strand

Reverse strand

Band

Transcripts

ENSMUST00000031519	ENSMUSP00000031519
ENSMUST00000112113	ENSMUSP00000107741
ENSMUST00000112112	ENSMUSP00000107740
ENSMUST00000112109	ENSMUSP00000107737
ENSMUST00000145197	ENSMUSP00000138183
ENSMUST00000151775

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	9 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005509	calcium ion binding
GO:0005515	protein binding
GO:0008139	nuclear localization sequence binding
GO:0019904	protein domain specific binding
GO:0031800	type 3 metabotropic glutamate receptor binding
GO:0042803	protein homodimerization activity
GO:0044325	ion channel binding
GO:0048306	calcium-dependent protein binding

Biological Process

GO:0010651	negative regulation of cell communication by electrical coupling
GO:0042308	negative regulation of protein import into nucleus
GO:1901385	regulation of voltage-gated calcium channel activity
GO:1901386	negative regulation of voltage-gated calcium channel activity

Cellular Component

GO:0000139	Golgi membrane
GO:0005615	extracellular space
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005856	cytoskeleton
GO:0005886	plasma membrane
GO:0009898	cytoplasmic side of plasma membrane
GO:0014069	postsynaptic density
GO:0030425	dendrite
GO:0043025	neuronal cell body
GO:0043234	protein complex
GO:0048471	perinuclear region of cytoplasm

Orthologs

Species

Homo sapiens

Bos taurus

Gene ID

Gene Order

ENSG00000157782

View Gene Order

ENSBTAG00000020049

Not yet available

Cross-References

SwissProt

TrEMBL

UniProt Splice Variant

Entrez Gene

UniGene

RefSeq

NM_013879 XM_006530374

OMIM

CCDS

CCDS19582

HPRD

IMGT

MGI ID

MGI Symbol

EMBL

GenPept

RNA Seq Atlas