Version 5.4
Mus musculus Gene: Tmem231
Summary
InnateDB Gene IDBG-193722.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tmem231
Gene Name transmembrane protein 231
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000031951
Encoded Proteins
IDBP-193724
transmembrane protein 231
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000205084:
This gene encodes a transmembrane protein, which is a component of the B9 complex involved in the formation of the diffusion barrier between the cilia and plasma membrane. Mutations in this gene cause Joubert syndrome (JBTS). Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:111912018-111933791
Strand Reverse strand
Band E1
Transcripts
ENSMUST00000034429 ENSMUSP00000034429
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0001701 in utero embryonic development
GO:0001944 vasculature development
GO:0007224 smoothened signaling pathway
GO:0032880 regulation of protein localization
GO:0042384 cilium assembly
GO:0042733 embryonic digit morphogenesis
GO:0043010 camera-type eye development
GO:0060563 neuroepithelial cell differentiation
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0035869 ciliary transition zone
GO:0036038 TCTN-B9D complex
GO:0060170 ciliary membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000205084
View Gene Order
ENSBTAG00000015432
Not yet available
Cross-References
SwissProt Q3U284
TrEMBL
UniProt Splice Variant
Entrez Gene 234740
UniGene Mm.414287
RefSeq NM_001033321
OMIM
CCDS CCDS52676
HPRD
IMGT
MGI ID MGI:2685024
MGI Symbol Tmem231
EMBL AK155425 BC100402 BC132428 BC132430
GenPept AAI00403 AAI32429 AAI32431 BAE33258
RNA Seq Atlas 234740

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca