Version 5.4
Mus musculus Gene: Msi1
Summary
InnateDB Gene IDBG-193777.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Msi1
Gene Name Musashi homolog 1(Drosophila)
Synonyms m-Msi-1; Msi1h; Musahi1
Species Mus musculus
Ensembl Gene ENSMUSG00000054256
Encoded Proteins
IDBP-193779
Musashi homolog 1(Drosophila)
IDBP-533289
Musashi homolog 1(Drosophila)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000135097:
This gene encodes a protein containing two conserved tandem RNA recognition motifs. Similar proteins in other species function as RNA-binding proteins and play central roles in posttranscriptional gene regulation. Expression of this gene has been correlated with the grade of the malignancy and proliferative activity in gliomas and melanomas. A pseudogene for this gene is located on chromosome 11q13. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:115429599-115455698
Strand Forward strand
Band F
Transcripts
ENSMUST00000067168 ENSMUSP00000070415
ENSMUST00000150779 ENSMUSP00000120516
ENSMUST00000151444
ENSMUST00000131079
ENSMUST00000145005
ENSMUST00000139918
ENSMUST00000145840
ENSMUST00000136586
ENSMUST00000130849
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 4 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003727 single-stranded RNA binding
GO:0008266 poly(U) RNA binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0009725 response to hormone
GO:0030855 epithelial cell differentiation
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005844 polysome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000135097
View Gene Order
ENSBTAG00000009800
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu03015
mRNA surveillance pathway pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa03015
mRNA surveillance pathway pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.391995 Mm.419870 Mm.5077
RefSeq NM_008629 XM_006530181 XM_006530182
OMIM
CCDS CCDS19591
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca