Version 5.4
Mus musculus Gene: Ehf
Summary
InnateDB Gene IDBG-193807.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ehf
Gene Name ets homologous factor
Synonyms 9030625L19Rik; AU019492
Species Mus musculus
Ensembl Gene ENSMUSG00000012350
Encoded Proteins
IDBP-193809
ets homologous factor
IDBP-258679
ets homologous factor
IDBP-258681
ets homologous factor
IDBP-534664
ets homologous factor
IDBP-540105
ets homologous factor
IDBP-536120
ets homologous factor
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000135373:
This gene encodes a protein that belongs to an ETS transcription factor subfamily characterized by epithelial-specific expression (ESEs). The encoded protein acts as a transcriptional repressor and may be involved in epithelial differentiation and carcinogenesis. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:103263433-103303278
Strand Reverse strand
Band E2
Transcripts
ENSMUST00000090475 ENSMUSP00000087961
ENSMUST00000111176 ENSMUSP00000106807
ENSMUST00000111174 ENSMUSP00000106805
ENSMUST00000137774
ENSMUST00000125788 ENSMUSP00000121103
ENSMUST00000140503 ENSMUSP00000114979
ENSMUST00000151265 ENSMUSP00000118275
ENSMUST00000128546
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0001077 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0006366 transcription from RNA polymerase II promoter
GO:0030154 cell differentiation
GO:0030855 epithelial cell differentiation
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000135373
View Gene Order
ENSBTAG00000017150
Not yet available
Cross-References
SwissProt
TrEMBL A2BIB6 B0S7M9
UniProt Splice Variant
Entrez Gene 13661
UniGene Mm.10724 Mm.403420
RefSeq NM_007914 XM_006498695 XM_006498696 XM_006498697 XM_006498698 XM_006498699 XM_006498700 XM_006498701 XM_006498702 XM_006498703 XM_006500756 XM_006500757 XM_006500758 XM_006500759 XM_006500760 XM_006500761 XM_006500762 XM_006500763 XM_006500764
OMIM
CCDS CCDS16475
HPRD
IMGT
MGI ID MGI:1270840
MGI Symbol Ehf
EMBL BX901906
GenPept
RNA Seq Atlas 13661

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca