Version 5.4
Mus musculus Gene: Avil
Summary
InnateDB Gene IDBG-193824.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Avil
Gene Name advillin
Synonyms Advil; DOC6
Species Mus musculus
Ensembl Gene ENSMUSG00000025432
Encoded Proteins
IDBP-193826
advillin
IDBP-536964
advillin
IDBP-539578
advillin
IDBP-536014
advillin
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000135407:
The protein encoded by this gene is a member of the gelsolin/villin family of actin regulatory proteins. This protein has structural similarity to villin. It binds actin and may play a role in the development of neuronal cells that form ganglia. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:127000709-127020994
Strand Forward strand
Band D3
Transcripts
ENSMUST00000026500 ENSMUSP00000026500
ENSMUST00000142698 ENSMUSP00000117667
ENSMUST00000126816 ENSMUSP00000115018
ENSMUST00000129173 ENSMUSP00000123405
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0005515 protein binding
Biological Process
GO:0007010 cytoskeleton organization
GO:0007015 actin filament organization
GO:0010976 positive regulation of neuron projection development
GO:0051693 actin filament capping
GO:0060271 cilium morphogenesis
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0030424 axon
GO:0042995 cell projection
GO:0043005 neuron projection
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000135407
View Gene Order
ENSBTAG00000016913
Not yet available
Cross-References
SwissProt O88398
TrEMBL D3YXP4 D3Z3N6 Q3TBC1
UniProt Splice Variant
Entrez Gene 11567
UniGene Mm.10739
RefSeq NM_009635 XM_006513102
OMIM
CCDS CCDS24221
HPRD
IMGT
MGI ID MGI:1333798
MGI Symbol Avil
EMBL AC134329 AF041448 AF059486 AK154851 AK155900 AK171324 BC120545 CH466578
GenPept AAC25050 AAC31808 AAI20546 BAE32877 BAE33492 BAE42393 EDL24458
RNA Seq Atlas 11567

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca