Homo sapiens Gene: TAS2R7
Summary
InnateDB Gene IDBG-19397.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TAS2R7
Gene Name taste receptor, type 2, member 7
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000121377
Encoded Proteins
taste receptor, type 2, member 7
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene product belongs to the family of candidate taste receptors that are members of the G-protein-coupled receptor superfamily. These proteins are specifically expressed in the taste receptor cells of the tongue and palate epithelia. They are organized in the genome in clusters and are genetically linked to loci that influence bitter perception in mice and humans. In functional expression studies, they respond to bitter tastants. This gene maps to the taste receptor gene cluster on chromosome 12p13. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:10801532-10802627
Strand Reverse strand
Band p13.2
Transcripts
ENST00000240687 ENSP00000240687
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004930 G-protein coupled receptor activity
GO:0008527 taste receptor activity
GO:0033038 bitter taste receptor activity
Biological Process
GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste
GO:0007186 G-protein coupled receptor signaling pathway
GO:0050909 sensory perception of taste
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Gene ID
Gene Order
Pathways
NETPATH
REACTOME
G alpha (i) signalling events pathway
Class C/3 (Metabotropic glutamate/pheromone receptors) pathway
Signaling by GPCR pathway
Signal Transduction pathway
GPCR downstream signaling pathway
GPCR ligand binding pathway
KEGG
Taste transduction pathway
INOH
PID NCI
Cross-References
SwissProt Q9NYW3
TrEMBL Q50KV5 Q50KV7
UniProt Splice Variant
Entrez Gene 50837
UniGene Hs.533754
RefSeq NM_023919
HUGO HGNC:14913
OMIM 604793
CCDS CCDS8631
HPRD
IMGT
EMBL AB199037 AB199038 AB199039 AF227133 AY724936 BC069091 BC093992 BC113561
GenPept AAF43906 AAH69091 AAH93992 AAI13562 AAU21138 BAD97941 BAD97942 BAD97943
RNA Seq Atlas 50837