Version 5.4
| Homo sapiens Protein: TAS2R7 | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-19399.5 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | TAS2R7 | ||||||||
| Protein Name | taste receptor, type 2, member 7 | ||||||||
| Synonyms | |||||||||
| Species | Homo sapiens | ||||||||
| Ensembl Protein | ENSP00000240687 | ||||||||
| InnateDB Gene | IDBG-19397 (TAS2R7) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5. | ||||||||
| Subcellular Localization | Membrane; Multi-pass membrane protein. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | Expressed in subsets of taste receptor cells of the tongue and palate epithelium and exclusively in gustducin- positive cells. | ||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | |||||||||
| InterPro |
IPR000276
G protein-coupled receptor, rhodopsin-like IPR007960 Mammalian taste receptor IPR017452 GPCR, rhodopsin-like, 7TM |
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| PFAM |
PF00001
PF05296 |
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| PRINTS |
PR00237
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| PIRSF | |||||||||
| SMART | |||||||||
| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | Q9NYW3 | ||||||||
| PhosphoSite | PhosphoSite-Q9NYW3 | ||||||||
| TrEMBL | Q50KV7 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 50837 | ||||||||
| UniGene | Hs.533754 | ||||||||
| RefSeq | NP_076408 | ||||||||
| HUGO | HGNC:14913 | ||||||||
| OMIM | 604793 | ||||||||
| CCDS | CCDS8631 | ||||||||
| HPRD | 16071 | ||||||||
| IMGT | |||||||||
| EMBL | AB199037 AB199038 AB199039 AF227133 AY724936 BC069091 BC093992 BC113561 | ||||||||
| GenPept | AAF43906 AAH69091 AAH93992 AAI13562 AAU21138 BAD97941 BAD97942 BAD97943 | ||||||||