Version 5.4
Mus musculus Gene: Bcl2l14
Summary
InnateDB Gene IDBG-194016.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Bcl2l14
Gene Name BCL2-like 14 (apoptosis facilitator)
Synonyms 4930452K23Rik; 4933405K19Rik; 9030625M01Rik; AI429211; Bclg
Species Mus musculus
Ensembl Gene ENSMUSG00000030200
Encoded Proteins
IDBP-194018
BCL2-like 14 (apoptosis facilitator)
IDBP-257021
BCL2-like 14 (apoptosis facilitator)
IDBP-534860
BCL2-like 14 (apoptosis facilitator)
IDBP-621004
BCL2-like 14 (apoptosis facilitator)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000121380:
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. Overexpression of this gene has been shown to induce apoptosis in cells. Three alternatively spliced transcript variants encoding two distinct isoforms have been reported for this gene. [provided by RefSeq, May 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:134396318-134438736
Strand Forward strand
Band G1
Transcripts
ENSMUST00000032321 ENSMUSP00000032321
ENSMUST00000111960 ENSMUSP00000107591
ENSMUST00000139183
ENSMUST00000127865 ENSMUSP00000115608
ENSMUST00000142612
ENSMUST00000163589 ENSMUSP00000132525
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0019901 protein kinase binding
Biological Process
GO:0006915 apoptotic process
GO:0042981 regulation of apoptotic process
GO:2001238 positive regulation of extrinsic apoptotic signaling pathway
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0043229 intracellular organelle
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000121380
View Gene Order
ENSBTAG00000047225
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
INOH
PID NCI
p53downstreampathway
Direct p53 effectors
Cross-References
SwissProt Q9CPT0
TrEMBL D3YZF2
UniProt Splice Variant
Entrez Gene 66813
UniGene Mm.474472
RefSeq NM_025778 XM_006506484
OMIM
CCDS CCDS20636
HPRD
IMGT
MGI ID MGI:1914063
MGI Symbol Bcl2l14
EMBL AC155838 AK008682 AK016670 AK016997 AK018579 AK160247 BC025541
GenPept AAH25541 BAB25830 BAB30370 BAB30545 BAB31290 BAE35712
RNA Seq Atlas 66813

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca