Version 5.4
| Mus musculus Gene: Ppp1r12b | |||||||
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| Summary | |||||||
| InnateDB Gene | IDBG-194175.6 | ||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
| Gene Symbol | Ppp1r12b | ||||||
| Gene Name | protein phosphatase 1, regulatory (inhibitor) subunit 12B | ||||||
| Synonyms | |||||||
| Species | Mus musculus | ||||||
| Ensembl Gene | ENSMUSG00000073557 | ||||||
| Encoded Proteins |
protein phosphatase 1, regulatory (inhibitor) subunit 12B
protein phosphatase 1, regulatory (inhibitor) subunit 12B
protein phosphatase 1, regulatory (inhibitor) subunit 12B
protein phosphatase 1, regulatory (inhibitor) subunit 12B
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| Protein Structure | |||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||
| Entrez Gene | |||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000077157:
Myosin phosphatase is a protein complex comprised of three subunits: a catalytic subunit (PP1c-delta, protein phosphatase 1, catalytic subunit delta), a large regulatory subunit (MYPT, myosin phosphatase target) and small regulatory subunit (sm-M20). Two isoforms of MYPT have been isolated--MYPT1 and MYPT2, the first of which is widely expressed, and the second of which may be specific to heart, skeletal muscle, and brain. Each of the MYPT isoforms functions to bind PP1c-delta and increase phosphatase activity. This locus encodes both MYTP2 and M20. Alternatively spliced transcript variants encoding different isoforms have been identified. Related pseudogenes have been defined on the Y chromosome. [provided by RefSeq, Oct 2011] |
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| Gene Information | |||||||
| Type | Protein coding | ||||||
| Genomic Location | Chromosome 1:134754658-134955942 | ||||||
| Strand | Reverse strand | ||||||
| Band | E4 | ||||||
| Transcripts | |||||||
| Interactions | |||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||
| NETPATH | |||||||
| REACTOME |
G2/M Transition pathway
Cell Cycle, Mitotic pathway
Cell Cycle pathway
Mitotic G2-G2/M phases pathway
Regulation of PLK1 Activity at G2/M Transition pathway
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| KEGG |
Regulation of actin cytoskeleton pathway
Focal adhesion pathway
Vascular smooth muscle contraction pathway
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| INOH | |||||||
| PID NCI | |||||||
| Pathway Predictions based on Human Orthology Data | |||||||
| NETPATH | |||||||
| REACTOME | |||||||
| KEGG |
Regulation of actin cytoskeleton pathway
Focal adhesion pathway
Vascular smooth muscle contraction pathway
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| INOH | |||||||
| PID NCI | |||||||
| Cross-References | |||||||
| SwissProt | |||||||
| TrEMBL | |||||||
| UniProt Splice Variant | |||||||
| Entrez Gene | |||||||
| UniGene | Mm.188709 Mm.451578 | ||||||
| RefSeq | NM_001081307 XM_006529710 | ||||||
| OMIM | |||||||
| CCDS | CCDS35717 | ||||||
| HPRD | |||||||
| IMGT | |||||||
| MGI ID | |||||||
| MGI Symbol | |||||||
| EMBL | |||||||
| GenPept | |||||||
| RNA Seq Atlas | |||||||