Version 5.4
Mus musculus Protein: Ppp1r12b
Summary
InnateDB Protein IDBP-194177.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ppp1r12b
Protein Name protein phosphatase 1, regulatory (inhibitor) subunit 12B
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000047463
InnateDB Gene IDBG-194175 (Ppp1r12b)
Protein Structure
UniProt Annotation
Function Regulates myosin phosphatase activity. Augments Ca(2+) sensitivity of the contractile apparatus (By similarity). {ECO:0000250}.
Subcellular Localization Cytoplasm {ECO:0000250}. Note=Along actomyosin filaments and stress fibers. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:1916417
InterPro IPR002110 Ankyrin repeat
IPR017401 Protein phosphatase 1, regulatory subunit 12A/B/C, eukaryote
IPR020683 Ankyrin repeat-containing domain
PFAM PF00023
PF13606
PF11929
PF12796
PRINTS PR01415
PIRSF PIRSF038141
SMART SM00248
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8BG95
PhosphoSite PhosphoSite-Q8BG95
TrEMBL
UniProt Splice Variant
Entrez Gene 329251
UniGene Mm.451578
RefSeq XP_006529773
MGI ID
MGI Symbol Ppp1r12b
OMIM
CCDS
HPRD
IMGT
EMBL AC117827 AC131591 AK007727 AK042847 AK046012 AK046167 AK080855
GenPept BAB25216 BAC31381 BAC32572 BAC32618 BAC38046

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca