InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Lgr6

Summary

InnateDB Gene

IDBG-194231.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Lgr6

Gene Name

leucine-rich repeat-containing G protein-coupled receptor 6

Synonyms

Species

Mus musculus

Ensembl Gene

ENSMUSG00000042793

Encoded Proteins

IDBP-194233

leucine-rich repeat-containing G protein-coupled receptor 6

IDBP-531957

leucine-rich repeat-containing G protein-coupled receptor 6

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000133067:
This gene encodes a member of the leucine-rich repeat-containing subgroup of the G protein-coupled 7-transmembrane protein superfamily. The encoded protein is a glycoprotein hormone receptor with a large N-terminal extracellular domain that contains leucine-rich repeats important for the formation of a horseshoe-shaped interaction motif for ligand binding. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 1:134983301-135105276

Strand

Reverse strand

Band

Transcripts

ENSMUST00000044828	ENSMUSP00000035444
ENSMUST00000137968	ENSMUSP00000122334
ENSMUST00000139369

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0004930	G-protein coupled receptor activity
GO:0005515	protein binding
GO:0016500	protein-hormone receptor activity

Biological Process

GO:0007186	G-protein coupled receptor signaling pathway
GO:0016055	Wnt signaling pathway
GO:0030177	positive regulation of Wnt signaling pathway
GO:0030335	positive regulation of cell migration