Version 5.4
Mus musculus Gene: Mesp1
Summary
InnateDB Gene IDBG-194334.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mesp1
Gene Name mesoderm posterior 1
Synonyms bHLHc5
Species Mus musculus
Ensembl Gene ENSMUSG00000030544
Encoded Proteins
IDBP-194336
mesoderm posterior 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 7:79792241-79793788
Strand Reverse strand
Band D2
Transcripts
ENSMUST00000032760 ENSMUSP00000032760
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0035326 enhancer binding
GO:0044212 transcription regulatory region DNA binding
GO:0046983 protein dimerization activity
Biological Process
GO:0001947 heart looping
GO:0003007 heart morphogenesis
GO:0003139 secondary heart field specification
GO:0003143 embryonic heart tube morphogenesis
GO:0003210 cardiac atrium formation
GO:0003211 cardiac ventricle formation
GO:0003236 sinus venosus morphogenesis
GO:0003241 growth involved in heart morphogenesis
GO:0003259 cardioblast anterior-lateral migration
GO:0003260 cardioblast migration
GO:0006351 transcription, DNA-templated
GO:0007219 Notch signaling pathway
GO:0007369 gastrulation
GO:0008078 mesodermal cell migration
GO:0022008 neurogenesis
GO:0023019 signal transduction involved in regulation of gene expression
GO:0035481 positive regulation of Notch signaling pathway involved in heart induction
GO:0042662 negative regulation of mesodermal cell fate specification
GO:0042664 negative regulation of endodermal cell fate specification
GO:0045446 endothelial cell differentiation
GO:0045747 positive regulation of Notch signaling pathway
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0048368 lateral mesoderm development
GO:0051155 positive regulation of striated muscle cell differentiation
GO:0055007 cardiac muscle cell differentiation
GO:0060913 cardiac cell fate determination
GO:0060921 sinoatrial node cell differentiation
GO:0060947 cardiac vascular smooth muscle cell differentiation
GO:0060975 cardioblast migration to the midline involved in heart field formation
GO:0070368 positive regulation of hepatocyte differentiation
GO:0090082 positive regulation of heart induction by negative regulation of canonical Wnt receptor signaling pathway
Cellular Component
GO:0005634 nucleus
Orthologs
No orthologs found for this gene
Cross-References
SwissProt P97309
TrEMBL
UniProt Splice Variant
Entrez Gene 17292
UniGene
RefSeq NM_008588
OMIM
CCDS CCDS21387
HPRD
IMGT
MGI ID MGI:107785
MGI Symbol Mesp1
EMBL BC125505 BC125507 D83674
GenPept AAI25506 AAI25508 BAA12041
RNA Seq Atlas 17292

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca