Version 5.4
Mus musculus Gene: Dtx3
Summary
InnateDB Gene IDBG-194473.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Dtx3
Gene Name deltex 3 homolog (Drosophila)
Synonyms Deltex3; mg310
Species Mus musculus
Ensembl Gene ENSMUSG00000040415
Encoded Proteins
IDBP-194475
deltex 3 homolog (Drosophila)
IDBP-274634
deltex 3 homolog (Drosophila)
IDBP-536735
deltex 3 homolog (Drosophila)
IDBP-537191
deltex 3 homolog (Drosophila)
IDBP-539111
deltex 3 homolog (Drosophila)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000178498:
DTX3 functions as an E3 ubiquitin ligase (Takeyama et al., 2003 [PubMed 12670957]).[supplied by OMIM, Nov 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:127190378-127195728
Strand Reverse strand
Band D3
Transcripts
ENSMUST00000038217 ENSMUSP00000044627
ENSMUST00000116229 ENSMUSP00000111937
ENSMUST00000130855 ENSMUSP00000114776
ENSMUST00000137151 ENSMUSP00000115302
ENSMUST00000144322 ENSMUSP00000116510
ENSMUST00000125254
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 17 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 17 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0016874 ligase activity
GO:0046872 metal ion binding
Biological Process
GO:0007219 Notch signaling pathway
GO:0016567 protein ubiquitination
Cellular Component
GO:0005575 cellular_component
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000178498
View Gene Order
ENSBTAG00000018002
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu04330
Notch signaling pathway pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa04330
Notch signaling pathway pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.271724
RefSeq NM_030714 XM_006514334 XM_006514337 XM_006514339
OMIM
CCDS CCDS36078
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca