Version 5.4
Mus musculus Gene: Pkd1l2
Summary
InnateDB Gene IDBG-194744.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pkd1l2
Gene Name polycystic kidney disease 1 like 2
Synonyms 1700126L06Rik
Species Mus musculus
Ensembl Gene ENSMUSG00000034416
Encoded Proteins
IDBP-194748
polycystic kidney disease 1 like 2
IDBP-263135
polycystic kidney disease 1 like 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000166473:
This gene encodes a member of the polycystin protein family. The encoded protein contains 11 transmembrane domains, a latrophilin/CL-1-like GPCR proteolytic site (GPS) domain, and a polycystin-1, lipoxygenase, alpha-toxin (PLAT) domain. This protein may function as a component of cation channel pores. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:116995679-117082449
Strand Reverse strand
Band E1
Transcripts
ENSMUST00000098375 ENSMUSP00000095977
ENSMUST00000109093 ENSMUSP00000104721
ENSMUST00000162080
ENSMUST00000160449
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005216 ion channel activity
GO:0005262 calcium channel activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0030246 carbohydrate binding
Biological Process
GO:0006811 ion transport
GO:0007218 neuropeptide signaling pathway
GO:0050982 detection of mechanical stimulus
GO:0055085 transmembrane transport
GO:0070588 calcium ion transmembrane transport
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000166473
View Gene Order
ENSBTAG00000012693
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.159753
RefSeq NM_029686 XM_006531487
OMIM
CCDS CCDS57646
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca