Version 5.4
Mus musculus Gene: Eif3m
Summary
InnateDB Gene IDBG-194825.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Eif3m
Gene Name eukaryotic translation initiation factor 3, subunit M
Synonyms Ga17; Pcid1; Tango7
Species Mus musculus
Ensembl Gene ENSMUSG00000027170
Encoded Proteins
IDBP-194827
eukaryotic translation initiation factor 3, subunit M
IDBP-258817
eukaryotic translation initiation factor 3, subunit M
IDBP-535360
eukaryotic translation initiation factor 3, subunit M
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000149100:
This gene encodes a protein that is part of the eurkaryotic translation initiation factor 3 complete (eIF-3) required for protein synthesis. Elevated levels of the encoded protein are present in cancer cell lines. Inactivation of the encoded protein has been shown to interfere with translation of herpes virus mRNAs by preventing the association of mRNAs with the ribosomes. A pseudogene of this gene is located on the X chromosome. [provided by RefSeq, Dec 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:104999656-105017080
Strand Reverse strand
Band E2
Transcripts
ENSMUST00000028592 ENSMUSP00000028592
ENSMUST00000111110 ENSMUSP00000106739
ENSMUST00000131266
ENSMUST00000148476 ENSMUSP00000122339
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 33 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 33 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003743 translation initiation factor activity
GO:0005488 binding
GO:0005515 protein binding
GO:0031369 translation initiation factor binding
Biological Process
GO:0001731 formation of translation preinitiation complex
GO:0002183 cytoplasmic translational initiation
GO:0006412 translation
GO:0006446 regulation of translational initiation
Cellular Component
GO:0005852 eukaryotic translation initiation factor 3 complex
GO:0016282 eukaryotic 43S preinitiation complex
GO:0033290 eukaryotic 48S preinitiation complex
GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000149100
View Gene Order
ENSBTAG00000005338
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_11
TCR pathway
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL A2A702
UniProt Splice Variant
Entrez Gene 98221
UniGene Mm.379278
RefSeq NM_145380
OMIM
CCDS CCDS16495
HPRD
IMGT
MGI ID MGI:1351744
MGI Symbol Eif3m
EMBL AL606494
GenPept CAM17235
RNA Seq Atlas 98221

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca