Mus musculus Gene: Bcmo1 | |||||||||
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Summary | |||||||||
InnateDB Gene | IDBG-194895.6 | ||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
Gene Symbol | Bcmo1 | ||||||||
Gene Name | beta-carotene 15,15'-monooxygenase | ||||||||
Synonyms | Bcdo; Bcdo1; Bcmo1; beta-CD; betaCMOOX; CMO1; Cmoi | ||||||||
Species | Mus musculus | ||||||||
Ensembl Gene | ENSMUSG00000031845 | ||||||||
Encoded Proteins |
beta-carotene 15,15'-monooxygenase
beta-carotene 15,15'-monooxygenase
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Protein Structure | |||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||
Entrez Gene | |||||||||
Summary |
Vitamin A metabolism is important for vital processes such as vision, embryonic development, cell differentiation, and membrane and skin protection. The protein encoded by this gene is a key enzyme in beta-carotene metabolism to vitamin A. It catalyzes the oxidative cleavage of beta,beta-carotene into two retinal molecules. Two alternatively spliced variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2009] |
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Gene Information | |||||||||
Type | Protein coding | ||||||||
Genomic Location | Chromosome 8:117095854-117133720 | ||||||||
Strand | Forward strand | ||||||||
Band | E1 | ||||||||
Transcripts |
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Interactions | |||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||
Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||
NETPATH | |||||||||
REACTOME |
Disease pathway
Retinoid metabolism and transport pathway
Visual phototransduction pathway
Signal Transduction pathway
Diseases associated with visual transduction pathway
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KEGG |
Retinol metabolism pathway
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INOH | |||||||||
PID NCI | |||||||||
Pathway Predictions based on Human Orthology Data | |||||||||
NETPATH | |||||||||
REACTOME |
Retinoid metabolism and transport pathway
Signal Transduction pathway
Diseases associated with visual transduction pathway
Visual phototransduction pathway
Disease pathway
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KEGG |
Retinol metabolism pathway
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INOH | |||||||||
PID NCI | |||||||||
Cross-References | |||||||||
SwissProt | |||||||||
TrEMBL | |||||||||
UniProt Splice Variant | |||||||||
Entrez Gene | |||||||||
UniGene | Mm.174133 | ||||||||
RefSeq | NM_001163028 NM_021486 | ||||||||
OMIM | |||||||||
CCDS | CCDS22697 CCDS52679 | ||||||||
HPRD | |||||||||
IMGT | |||||||||
MGI ID | |||||||||
MGI Symbol | |||||||||
EMBL | |||||||||
GenPept | |||||||||
RNA Seq Atlas | |||||||||