Mus musculus Gene: Bcmo1
Summary
InnateDB Gene IDBG-194895.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Bcmo1
Gene Name beta-carotene 15,15'-monooxygenase
Synonyms Bcdo; Bcdo1; Bcmo1; beta-CD; betaCMOOX; CMO1; Cmoi
Species Mus musculus
Ensembl Gene ENSMUSG00000031845
Encoded Proteins
beta-carotene 15,15'-monooxygenase
beta-carotene 15,15'-monooxygenase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Vitamin A metabolism is important for vital processes such as vision, embryonic development, cell differentiation, and membrane and skin protection. The protein encoded by this gene is a key enzyme in beta-carotene metabolism to vitamin A. It catalyzes the oxidative cleavage of beta,beta-carotene into two retinal molecules. Two alternatively spliced variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:117095854-117133720
Strand Forward strand
Band E1
Transcripts
ENSMUST00000034308 ENSMUSP00000034308
ENSMUST00000167370 ENSMUSP00000132042
ENSMUST00000176860 ENSMUSP00000134815
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003834 beta-carotene 15,15'-monooxygenase activity
GO:0004497 monooxygenase activity
GO:0046872 metal ion binding
Biological Process
GO:0001523 retinoid metabolic process
GO:0042572 retinol metabolic process
GO:0055114 oxidation-reduction process
Cellular Component
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Disease pathway
Retinoid metabolism and transport pathway
Visual phototransduction pathway
Signal Transduction pathway
Diseases associated with visual transduction pathway
KEGG
Retinol metabolism pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Retinoid metabolism and transport pathway
Signal Transduction pathway
Diseases associated with visual transduction pathway
Visual phototransduction pathway
Disease pathway
KEGG
Retinol metabolism pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.174133
RefSeq NM_001163028 NM_021486
OMIM
CCDS CCDS22697 CCDS52679
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas