Version 5.4
Mus musculus Gene: Arhgap9
Summary
InnateDB Gene IDBG-194966.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Arhgap9
Gene Name Rho GTPase activating protein 9
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000040345
Encoded Proteins
IDBP-194970
Rho GTPase activating protein 9
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000123329:
This gene encodes a member of the Rho-GAP family of GTPase activating proteins. The protein has substantial GAP activity towards several Rho-family GTPases in vitro, converting them to an inactive GDP-bound state. It is implicated in regulating adhesion of hematopoietic cells to the extracellular matrix. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:127323727-127329943
Strand Forward strand
Band D3
Transcripts
ENSMUST00000069548 ENSMUSP00000066455
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005096 GTPase activator activity
GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding
Biological Process
GO:0007165 signal transduction
GO:0043547 positive regulation of GTPase activity
Cellular Component
GO:0005575 cellular_component
GO:0005622 intracellular
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000123329
View Gene Order
ENSBTAG00000018403
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_11051
Rho GTPase cycle pathway
REACT_11044
Signaling by Rho GTPases pathway
REACT_111102
Signal Transduction pathway
KEGG
INOH
PID NCI
rac1_reg_pathway
Regulation of RAC1 activity
rhoa_reg_pathway
Regulation of RhoA activity
Cross-References
SwissProt
TrEMBL Q1HDU4 Q78T58 Q8C8F0 Q8QZW8
UniProt Splice Variant
Entrez Gene 216445
UniGene Mm.227198
RefSeq NM_001285785 NM_146011 XM_006513570
OMIM
CCDS CCDS36079
HPRD
IMGT
MGI ID MGI:2143764
MGI Symbol Arhgap9
EMBL AC114678 AK047280 AK049245 AK089051 BC024535 BC027374 DQ498128
GenPept AAH24535 AAH27374 ABF48400 BAC33014 BAC33633 BAC40720
RNA Seq Atlas 216445

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca