Version 5.4
Mus musculus Gene: Wbp11
Summary
InnateDB Gene IDBG-195017.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Wbp11
Gene Name WW domain binding protein 11
Synonyms 2510026P17Rik; D6Wsu113e; Npwbp; SIPP1
Species Mus musculus
Ensembl Gene ENSMUSG00000030216
Encoded Proteins
IDBP-273936
WW domain binding protein 11
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000084463:
This gene encodes a nuclear protein, which colocalizes with mRNA splicing factors and intermediate filament-containing perinuclear networks. This protein has 95% amino acid sequence identity to the mouse Wbp11 protein. It contains two proline-rich regions that bind to the WW domain of Npw38, a nuclear protein, and thus this protein is also called Npw38-binding protein NpwBP. The Npw38-NpwBP complex may function as a component of an mRNA factory in the nucleus. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:136813654-136828233
Strand Reverse strand
Band G1
Transcripts
ENSMUST00000116514 ENSMUSP00000112213
ENSMUST00000151333
ENSMUST00000127178
ENSMUST00000129078
ENSMUST00000141598
ENSMUST00000146348
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 29 interaction(s) predicted by orthology.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 29 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008599 protein phosphatase type 1 regulator activity
GO:0044822 poly(A) RNA binding
GO:0050699 WW domain binding
Biological Process
GO:0006364 rRNA processing
GO:0006396 RNA processing
GO:0006397 mRNA processing
GO:0008380 RNA splicing
GO:0050790 regulation of catalytic activity
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0016607 nuclear speck
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000084463
View Gene Order
ENSBTAG00000014759
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu03040
Spliceosome pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa03040
Spliceosome pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.141197 Mm.399530 Mm.410141 Mm.412991
RefSeq NM_021714 XM_006506448
OMIM
CCDS CCDS20655
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca