Homo sapiens Gene: TAS2R10
Summary
InnateDB Gene IDBG-19518.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TAS2R10
Gene Name taste receptor, type 2, member 10
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000121318
Encoded Proteins
taste receptor, type 2, member 10
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene product belongs to the family of candidate taste receptors that are members of the G-protein-coupled receptor superfamily. These proteins are specifically expressed in the taste receptor cells of the tongue and palate epithelia. They are organized in the genome in clusters and are genetically linked to loci that influence bitter perception in mice and humans. In functional expression studies, they respond to bitter tastants. This gene maps to the taste receptor gene cluster on chromosome 12p13. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:10825317-10826358
Strand Reverse strand
Band p13.2
Transcripts
ENST00000240619 ENSP00000240619
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004930 G-protein coupled receptor activity
GO:0008527 taste receptor activity
GO:0033038 bitter taste receptor activity
Biological Process
GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste
GO:0007186 G-protein coupled receptor signaling pathway
GO:0050909 sensory perception of taste
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
G alpha (i) signalling events pathway
Class C/3 (Metabotropic glutamate/pheromone receptors) pathway
Signaling by GPCR pathway
Signal Transduction pathway
GPCR downstream signaling pathway
GPCR ligand binding pathway
KEGG
Taste transduction pathway
INOH
PID NCI
Cross-References
SwissProt Q9NYW0
TrEMBL Q50KS2
UniProt Splice Variant
Entrez Gene 50839
UniGene Hs.533756
RefSeq NM_023921 XM_006719082 XM_006725535 XM_006726236
HUGO HGNC:14918
OMIM 604791
CCDS CCDS8634
HPRD 11990
IMGT
EMBL AB199075 AC006518 AF227136 AY724946 BC069089 BC101762 BC101764
GenPept AAF43909 AAH69089 AAI01763 AAI01765 AAU21148 BAD97976
RNA Seq Atlas 50839