InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: TAS2R10

Summary

InnateDB Protein

IDBP-19520.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

TAS2R10

Protein Name

taste receptor, type 2, member 10

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000240619

InnateDB Gene

IDBG-19518 (TAS2R10)

Protein Structure

UniProt Annotation

Function

Gustducin-coupled strychnine receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium- regulated cation channel TRPM5. {ECO:0000269PubMed:15759003}.

Subcellular Localization

Membrane; Multi-pass membrane protein.

Disease Associations

Tissue Specificity

Expressed in subsets of taste receptor cells of the tongue and palate epithelium and exclusively in gustducin- positive cells.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004930	G-protein coupled receptor activity
GO:0008527	taste receptor activity
GO:0033038	bitter taste receptor activity

Biological Process

GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste
GO:0007186	G-protein coupled receptor signaling pathway
GO:0050909	sensory perception of taste