Version 5.4
Mus musculus Gene: Nek11
Summary
InnateDB Gene IDBG-195195.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Nek11
Gene Name NIMA (never in mitosis gene a)-related expressed kinase 11
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000035032
Encoded Proteins
IDBP-195197
NIMA (never in mitosis gene a)-related expressed kinase 11
IDBP-534020
NIMA (never in mitosis gene a)-related expressed kinase 11
IDBP-532584
NIMA (never in mitosis gene a)-related expressed kinase 11
IDBP-742315
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000114670:
This gene encodes a member of the never in mitosis gene A family of kinases. The encoded protein localizes to the nucleoli, and may function with NEK2A in the S-phase checkpoint. The encoded protein appears to play roles in DNA replication and response to genotoxic stress. Alternatively spliced transcript variants have been described.[provided by RefSeq, Mar 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:105162156-105395524
Strand Reverse strand
Band F1
Transcripts
ENSMUST00000038648 ENSMUSP00000038611
ENSMUST00000156256 ENSMUSP00000116761
ENSMUST00000140851 ENSMUSP00000116864
ENSMUST00000177029 ENSMUSP00000135837
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
GO:0046872 metal ion binding
Biological Process
GO:0006468 protein phosphorylation
GO:0008152 metabolic process
GO:0031572 G2 DNA damage checkpoint
GO:0031573 intra-S DNA damage checkpoint
GO:0035556 intracellular signal transduction
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000114670
View Gene Order
ENSBTAG00000009258
Not yet available
Cross-References
SwissProt
TrEMBL D3Z1E7
UniProt Splice Variant
Entrez Gene 208583
UniGene Mm.347509
RefSeq NM_172461 XM_006511679 XM_006511681 XM_006511682 XM_006511683 XM_006511684 XM_006511687
OMIM
CCDS CCDS23464
HPRD
IMGT
MGI ID MGI:2442276
MGI Symbol Nek11
EMBL AC113016 AC161250
GenPept
RNA Seq Atlas 208583

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca