Version 5.4
Bos taurus Gene: NEK11
Summary
InnateDB Gene IDBG-639100.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NEK11
Gene Name Uncharacterized protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000009258
Encoded Proteins
IDBP-691227
NIMA (never in mitosis gene a)- related kinase 11
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000114670:
This gene encodes a member of the never in mitosis gene A family of kinases. The encoded protein localizes to the nucleoli, and may function with NEK2A in the S-phase checkpoint. The encoded protein appears to play roles in DNA replication and response to genotoxic stress. Alternatively spliced transcript variants have been described.[provided by RefSeq, Mar 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:140061251-140332232
Strand Reverse strand
Band
Transcripts
ENSBTAT00000012197 ENSBTAP00000012197
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0006468 protein phosphorylation
GO:0031572 G2 DNA damage checkpoint
GO:0031573 intra-S DNA damage checkpoint
GO:0035556 intracellular signal transduction
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000114670
View Gene Order
ENSMUSG00000035032
View Gene Order
Cross-References
SwissProt
TrEMBL E1BJU4
UniProt Splice Variant
Entrez Gene 614924
UniGene
RefSeq XM_002685106 XM_866575
HUGO HGNC:18593
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02003159 DAAA02003160 DAAA02003161 DAAA02003162 DAAA02003163 DAAA02003164 DAAA02003165 DAAA02003166 DAAA02003167 DAAA02003168 DAAA02003169 DAAA02003170
GenPept
RNA Seq Atlas 614924

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca