Version 5.4
Mus musculus Gene: Crtc3
Summary
InnateDB Gene IDBG-195478.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Crtc3
Gene Name CREB regulated transcription coactivator 3
Synonyms 2610312F20Rik; 6332415K15Rik; AI429792; BC011210; TORC3
Species Mus musculus
Ensembl Gene ENSMUSG00000030527
Encoded Proteins
IDBP-400510
CREB regulated transcription coactivator 3
IDBP-542022
CREB regulated transcription coactivator 3
IDBP-542438
CREB regulated transcription coactivator 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000140577:
This gene is a member of the CREB regulated transcription coactivator gene family. This family regulates CREB-dependent gene transcription in a phosphorylation-independent manner and may be selective for cAMP-responsive genes. The protein encoded by this gene may induce mitochondrial biogenesis and attenuate catecholamine signaling in adipose tissue. A translocation event between this gene and Notch coactivator mastermind-like gene 2, which results in a fusion protein, has been reported in mucoepidermoid carcinomas. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jul 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:80586627-80688877
Strand Reverse strand
Band D3
Transcripts
ENSMUST00000122255 ENSMUSP00000113540
ENSMUST00000149176 ENSMUSP00000123107
ENSMUST00000127182
ENSMUST00000127326 ENSMUSP00000117255
ENSMUST00000154761
ENSMUST00000152668
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0008140 cAMP response element binding protein binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0032793 positive regulation of CREB transcription factor activity
GO:0043951 negative regulation of cAMP-mediated signaling
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0050995 negative regulation of lipid catabolic process
GO:0051289 protein homotetramerization
GO:0097009 energy homeostasis
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000140577
View Gene Order
ENSBTAG00000010915
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.392175
RefSeq NM_173863 XM_006541195 XM_006541196
OMIM
CCDS CCDS21398
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca