Version 5.4
Mus musculus Gene: Capza3
Summary
InnateDB Gene IDBG-195860.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Capza3
Gene Name capping protein (actin filament) muscle Z-line, alpha 3
Synonyms 510-4; Cappa3; Gsg3; repro32; Tex8
Species Mus musculus
Ensembl Gene ENSMUSG00000041791
Encoded Proteins
IDBP-195862
capping protein (actin filament) muscle Z-line, alpha 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000177938:
This gene encodes an actin capping protein, one of the F-actin capping protein alpha subunit family. The encoded protein is predominantly localized to the neck region of ejaculated sperm, other immunohistochemical signals were found in the tail and postacrosomal regions. The encoded protein may also form heterodimers of alpha and beta subunits. This protein may be important in determining sperm architecture and male fertility. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:140041557-140042778
Strand Forward strand
Band G2
Transcripts
ENSMUST00000043797 ENSMUSP00000038562
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
Biological Process
GO:0007286 spermatid development
GO:0030036 actin cytoskeleton organization
GO:0051693 actin filament capping
Cellular Component
GO:0001669 acrosomal vesicle
GO:0005634 nucleus
GO:0008290 F-actin capping protein complex
GO:0016020 membrane
GO:0030863 cortical cytoskeleton
GO:0071203 WASH complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000177938
View Gene Order
ENSBTAG00000013207
Not yet available
Cross-References
SwissProt P70190
TrEMBL
UniProt Splice Variant
Entrez Gene 12344
UniGene Mm.12817
RefSeq NM_007605
OMIM
CCDS CCDS20672
HPRD
IMGT
MGI ID MGI:106221
MGI Symbol Capza3
EMBL AB026984 AK016391 BC049620 D87471
GenPept AAH49620 BAA13409 BAA81887 BAB30213
RNA Seq Atlas 12344

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca