Version 5.4
Mus musculus Gene: Ap3b2
Summary
InnateDB Gene IDBG-196186.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ap3b2
Gene Name adaptor-related protein complex 3, beta 2 subunit
Synonyms [b]-NAP; AI549966; AU042881; beta-NAP; beta3B; Naptb
Species Mus musculus
Ensembl Gene ENSMUSG00000062444
Encoded Proteins
IDBP-196188
adaptor-related protein complex 3, beta 2 subunit
IDBP-400493
adaptor-related protein complex 3, beta 2 subunit
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000103723:
Adaptor protein-3 (AP3) is a heterotetrameric vesicle-coat protein complex. Some AP3 subunits are ubiquitously expressed, whereas others are expressed exclusively in neurons. The neuron-specific AP3 complex, which includes AP3B2, is thought to serve neuron-specific functions such as neurotransmitter release (Grabner et al., 2006 [PubMed 16788073]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:81460399-81493925
Strand Reverse strand
Band D3
Transcripts
ENSMUST00000082090 ENSMUSP00000080739
ENSMUST00000119121 ENSMUSP00000114032
ENSMUST00000147624
ENSMUST00000152355
ENSMUST00000125634
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005488 binding
Biological Process
GO:0006886 intracellular protein transport
GO:0008089 anterograde axon cargo transport
GO:0016192 vesicle-mediated transport
GO:0048490 anterograde synaptic vesicle transport
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005802 trans-Golgi network
GO:0030117 membrane coat
GO:0030123 AP-3 adaptor complex
GO:0030665 clathrin-coated vesicle membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000103723
View Gene Order
ENSBTAG00000008495
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu04142
Lysosome pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa04142
Lysosome pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.322894
RefSeq NM_021492
OMIM
CCDS CCDS21403
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca