Version 5.4
Mus musculus Gene: Fbxo31
Summary
InnateDB Gene IDBG-196644.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Fbxo31
Gene Name F-box protein 31
Synonyms 1110003O08Rik; 2310046N15Rik; Fbx14; Fbxo14
Species Mus musculus
Ensembl Gene ENSMUSG00000052934
Encoded Proteins
IDBP-196646
RIKEN cDNA 1110003O08 gene
IDBP-717820
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000103264:
Members of the F-box protein family, such as FBXO31, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:121549440-121578806
Strand Reverse strand
Band E1
Transcripts
ENSMUST00000059018 ENSMUSP00000057573
ENSMUST00000180979
ENSMUST00000180539
ENSMUST00000181663 ENSMUSP00000137907
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0030332 cyclin binding
Biological Process
GO:0006974 cellular response to DNA damage stimulus
GO:0008054 cyclin catabolic process
GO:0016567 protein ubiquitination
GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0031571 mitotic G1 DNA damage checkpoint
Cellular Component
GO:0019005 SCF ubiquitin ligase complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000103264
View Gene Order
ENSBTAG00000002226
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.24829 Mm.485213
RefSeq NM_133765 XM_006531477 XM_006531478
OMIM
CCDS CCDS52693
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca