Version 5.4
Mus musculus Gene: Pdha2
Summary
InnateDB Gene IDBG-196879.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pdha2
Gene Name pyruvate dehydrogenase E1 alpha 2
Synonyms Pdhal
Species Mus musculus
Ensembl Gene ENSMUSG00000047674
Encoded Proteins
IDBP-196881
pyruvate dehydrogenase E1 alpha 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 3:141210004-141212355
Strand Reverse strand
Band H1
Transcripts
ENSMUST00000057860 ENSMUSP00000060774
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity
GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
Biological Process
GO:0006006 glucose metabolic process
GO:0006090 pyruvate metabolic process
GO:0006096 glycolytic process
GO:0006099 tricarboxylic acid cycle
GO:0008152 metabolic process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0043231 intracellular membrane-bounded organelle
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
KEGG
mmu00020
Citrate cycle (TCA cycle) pathway
mmu00010
Glycolysis / Gluconeogenesis pathway
mmu00620
Pyruvate metabolism pathway
INOH
PID NCI
Cross-References
SwissProt P35487
TrEMBL
UniProt Splice Variant
Entrez Gene 18598
UniGene Mm.399543 Mm.4223
RefSeq NM_008811
OMIM
CCDS CCDS17872
HPRD
IMGT
MGI ID MGI:97533
MGI Symbol Pdha2
EMBL AK076791 BC100460 M76728
GenPept AAA53047 AAI00461 BAC36482
RNA Seq Atlas 18598

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca