InnateDB Protein
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IDBP-196881.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Pdha2
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Protein Name
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pyruvate dehydrogenase E1 alpha 2
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Synonyms
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Pdhal;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000060774
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InnateDB Gene
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IDBG-196879 (Pdha2)
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Protein Structure
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Function |
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle. {ECO:0000250}.
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Subcellular Localization |
Mitochondrion matrix {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
Testis.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
1
[view]
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Protein-Protein |
0
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Protein-DNA |
1
[view]
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
Accession |
GO Term |
GO:0004739
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pyruvate dehydrogenase (acetyl-transferring) activity
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GO:0016624
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oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:97533
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InterPro |
IPR001017
Dehydrogenase, E1 component
IPR017597
Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y
IPR029061
Thiamin diphosphate-binding fold
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PFAM |
PF00676
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
P35487
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PhosphoSite |
PhosphoSite-P35487
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
18598
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UniGene |
Mm.4223
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RefSeq |
NP_032837
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MGI ID |
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MGI Symbol |
Pdha2
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OMIM |
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CCDS |
CCDS17872
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HPRD |
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IMGT |
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EMBL |
AK076791
BC100460
M76728
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GenPept |
AAA53047
AAI00461
BAC36482
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