Version 5.4
Mus musculus Gene: Il22ra1
Summary
InnateDB Gene IDBG-197189.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Il22ra1
Gene Name interleukin 22 receptor, alpha 1
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000037157
Encoded Proteins
IDBP-197191
interleukin 22 receptor, alpha 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000142677:
The protein encoded by this gene belongs to the class II cytokine receptor family, and has been shown to be a receptor for interleukin 22 (IL22). IL22 receptor is a protein complex that consists of this protein and interleukin 10 receptor, beta (IL10BR/CRFB4), a subunit also shared by the receptor complex for interleukin 10 (IL10). This gene and interleukin 28 receptor, alpha (IL28RA) form a cytokine receptor gene cluster in the chromosomal region 1p36. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:135728172-135752140
Strand Forward strand
Band D3
Transcripts
ENSMUST00000102546 ENSMUSP00000099605
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0042015 interleukin-20 binding
Biological Process
GO:0050829 defense response to Gram-negative bacterium
Cellular Component
GO:0005575 cellular_component
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000142677
View Gene Order
ENSBTAG00000001100
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu04060
Cytokine-cytokine receptor interaction pathway
mmu04630
Jak-STAT signaling pathway pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa04060
Cytokine-cytokine receptor interaction pathway
hsa04630
Jak-STAT signaling pathway pathway
INOH
PID NCI
Cross-References
SwissProt Q80XZ4
TrEMBL
UniProt Splice Variant
Entrez Gene 230828
UniGene Mm.261647
RefSeq NM_178257
OMIM
CCDS CCDS18789
HPRD
IMGT
MGI ID MGI:2663588
MGI Symbol Il22ra1
EMBL AK141289 AL662911 AY103454 BC140972 BC140973
GenPept AAI40973 AAI40974 AAM52222 BAE24639 CAM13650
RNA Seq Atlas 230828

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca