Version 5.4
Mus musculus Gene: Slc39a5
Summary
InnateDB Gene IDBG-197401.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Slc39a5
Gene Name solute carrier family 39 (metal ion transporter), member 5
Synonyms 1810013D05Rik; 2010205A06Rik; Zip5
Species Mus musculus
Ensembl Gene ENSMUSG00000039878
Encoded Proteins
IDBP-197405
solute carrier family 39 (metal ion transporter), member 5
IDBP-620630
solute carrier family 39 (metal ion transporter), member 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000139540:
Zinc is an essential cofactor for hundreds of enzymes. It is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, as well as in the control of gene transcription, growth, development, and differentiation. SLC39A5 belongs to a subfamily of proteins that show structural characteristics of zinc transporters (Taylor and Nicholson, 2003 [PubMed 12659941]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:128395934-128401224
Strand Reverse strand
Band D3
Transcripts
ENSMUST00000042666 ENSMUSP00000037753
ENSMUST00000167859 ENSMUSP00000131736
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0046873 metal ion transmembrane transporter activity
Biological Process
GO:0006829 zinc ion transport
GO:0006882 cellular zinc ion homeostasis
GO:0030001 metal ion transport
GO:0034224 cellular response to zinc ion starvation
GO:0055085 transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016323 basolateral plasma membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000139540
View Gene Order
ENSBTAG00000002799
Not yet available
Pathways
NETPATH
REACTOME
REACT_217615
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds pathway
REACT_247550
SLC-mediated transmembrane transport pathway
REACT_198240
Zinc influx into cells by the SLC39 gene family pathway
REACT_243781
Zinc transporters pathway
REACT_253400
Transmembrane transport of small molecules pathway
REACT_251299
Metal ion SLC transporters pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_20603
Zinc influx into cells by the SLC39 gene family pathway
REACT_20547
Metal ion SLC transporters pathway
REACT_19305
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_20530
Zinc transporters pathway
REACT_19118
SLC-mediated transmembrane transport pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q9D856
TrEMBL
UniProt Splice Variant
Entrez Gene 72002
UniGene Mm.22983
RefSeq NM_001136237 NM_028051 NM_028092 XM_006514173
OMIM
CCDS CCDS24275
HPRD
IMGT
MGI ID MGI:1919336
MGI Symbol Slc39a5
EMBL AK007473 AK008448 BC028990
GenPept AAH28990 BAB25054 BAB25675
RNA Seq Atlas 72002

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca