Version 5.4
Mus musculus Gene: Pkn2
Summary
InnateDB Gene IDBG-197436.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pkn2
Gene Name protein kinase N2
Synonyms 6030436C20Rik; AI507382; PRK2; Prkcl2; Stk7
Species Mus musculus
Ensembl Gene ENSMUSG00000004591
Encoded Proteins
IDBP-197440
protein kinase N2
IDBP-621337
protein kinase N2
IDBP-621339
protein kinase N2
IDBP-621341
protein kinase N2
IDBP-621347
protein kinase N2
IDBP-621349
protein kinase N2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000065243:
Gene Information
Type Protein coding
Genomic Location Chromosome 3:142790902-142882004
Strand Reverse strand
Band H1
Transcripts
ENSMUST00000043812 ENSMUSP00000039566
ENSMUST00000173913 ENSMUSP00000134046
ENSMUST00000174422 ENSMUSP00000134559
ENSMUST00000173830 ENSMUSP00000133691
ENSMUST00000166330
ENSMUST00000172521
ENSMUST00000173615 ENSMUSP00000133419
ENSMUST00000174169
ENSMUST00000174680 ENSMUSP00000134041
ENSMUST00000174099
ENSMUST00000172916
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 26 interaction(s) predicted by orthology.
Predicted by orthology
Total 26 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004697 protein kinase C activity
GO:0004713 protein tyrosine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
GO:0042826 histone deacetylase binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006468 protein phosphorylation
GO:0006915 apoptotic process
GO:0007049 cell cycle
GO:0007155 cell adhesion
GO:0007165 signal transduction
GO:0010631 epithelial cell migration
GO:0032467 positive regulation of cytokinesis
GO:0043297 apical junction assembly
GO:0045931 positive regulation of mitotic cell cycle
GO:0051301 cell division
GO:2000145 regulation of cell motility
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005856 cytoskeleton
GO:0016020 membrane
GO:0030027 lamellipodium
GO:0030496 midbody
GO:0032154 cleavage furrow
GO:0043296 apical junction complex
GO:0045111 intermediate filament cytoskeleton
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000065243
View Gene Order
ENSBTAG00000021900
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_4
EGFR1 pathway
REACTOME
KEGG
INOH
PID NCI
rhoa_pathway
RhoA signaling pathway
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.244236 Mm.398767 Mm.405430 Mm.413488
RefSeq NM_178654
OMIM
CCDS CCDS51084
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca