Version 5.4
Mus musculus Gene: Myl6b
Summary
InnateDB Gene IDBG-197665.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Myl6b
Gene Name myosin, light polypeptide 6B
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000039824
Encoded Proteins
IDBP-197667
myosin, light polypeptide 6B
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000196465:
Myosin is a hexameric ATPase cellular motor protein. It is composed of two heavy chains, two nonphosphorylatable alkali light chains, and two phosphorylatable regulatory light chains. This gene encodes a myosin alkali light chain expressed in both slow-twitch skeletal muscle and in nonmuscle tissue. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:128494157-128498685
Strand Reverse strand
Band D3
Transcripts
ENSMUST00000026428 ENSMUSP00000026428
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 16 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003774 motor activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0008307 structural constituent of muscle
Biological Process
GO:0006936 muscle contraction
GO:0007519 skeletal muscle tissue development
GO:0008152 metabolic process
GO:0030049 muscle filament sliding
Cellular Component
GO:0016459 myosin complex
GO:0016461 unconventional myosin complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000196465
View Gene Order
ENSBTAG00000031217
Not yet available
Pathways
NETPATH
REACTOME
REACT_235059
Smooth Muscle Contraction pathway
REACT_262759
Muscle contraction pathway
KEGG
mmu04270
Vascular smooth muscle contraction pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_20558
Smooth Muscle Contraction pathway
REACT_17044
Muscle contraction pathway
KEGG
hsa04270
Vascular smooth muscle contraction pathway
INOH
PID NCI
Cross-References
SwissProt Q8CI43
TrEMBL
UniProt Splice Variant
Entrez Gene 216459
UniGene
RefSeq NM_172259 XM_006513573 XM_006513574 XM_006513575 XM_006513576
OMIM
CCDS CCDS24279
HPRD
IMGT
MGI ID MGI:1917789
MGI Symbol Myl6b
EMBL BC037527
GenPept AAH37527
RNA Seq Atlas 216459

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca