Version 5.4
Mus musculus Gene: Tusc2
Summary
InnateDB Gene IDBG-197694.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tusc2
Gene Name tumor suppressor candidate 2
Synonyms 1190001E22Rik; AA407686; Fus1; Lgcc; PAP; Pdap2
Species Mus musculus
Ensembl Gene ENSMUSG00000010054
Encoded Proteins
IDBP-197696
tumor suppressor candidate 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000114383:
This gene is a highly conserved lung cancer candidate gene. No other information about this gene is currently available. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:107563255-107566108
Strand Forward strand
Band F1
Transcripts
ENSMUST00000010198 ENSMUSP00000010198
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0001779 natural killer cell differentiation
GO:0006909 phagocytosis
GO:0006954 inflammatory response
GO:0032618 interleukin-15 production
GO:0032700 negative regulation of interleukin-17 production
GO:0032733 positive regulation of interleukin-10 production
GO:0048469 cell maturation
GO:0050829 defense response to Gram-negative bacterium
GO:0051881 regulation of mitochondrial membrane potential
GO:0052567 response to defense-related host reactive oxygen species production
GO:0070945 neutrophil mediated killing of gram-negative bacterium
GO:0071609 chemokine (C-C motif) ligand 5 production
GO:2000377 regulation of reactive oxygen species metabolic process
Cellular Component
GO:0005739 mitochondrion
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000114383
View Gene Order
ENSBTAG00000020962
Not yet available
Cross-References
SwissProt Q9WVF8
TrEMBL Q542N4
UniProt Splice Variant
Entrez Gene 80385
UniGene Mm.21739
RefSeq NM_019742
OMIM
CCDS CCDS23495
HPRD
IMGT
MGI ID MGI:1931086
MGI Symbol Tusc2
EMBL AF123387 AK004430 AK082684 BC048477 CH466560
GenPept AAD42286 AAH48477 BAB23300 BAC38571 EDL21200
RNA Seq Atlas 80385

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca