Version 5.4
Mus musculus Gene: Ppfibp1
Summary
InnateDB Gene IDBG-198603.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ppfibp1
Gene Name PTPRF interacting protein, binding protein 1 (liprin beta 1)
Synonyms 4632409B19Rik; AW214454; AW261454
Species Mus musculus
Ensembl Gene ENSMUSG00000016487
Encoded Proteins
IDBP-198605
PTPRF interacting protein, binding protein 1 (liprin beta 1)
IDBP-257710
PTPRF interacting protein, binding protein 1 (liprin beta 1)
IDBP-541181
PTPRF interacting protein, binding protein 1 (liprin beta 1)
IDBP-541653
PTPRF interacting protein, binding protein 1 (liprin beta 1)
IDBP-541649
PTPRF interacting protein, binding protein 1 (liprin beta 1)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000110841:
The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. It has been proposed that liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR family of tyrosine phosphatases. This protein was found to interact with S100A4, a calcium-binding protein related to tumor invasiveness and metastasis. In vitro experiment demonstrated that the interaction inhibited the phosphorylation of this protein by protein kinase C and protein kinase CK2. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:146888487-147032025
Strand Forward strand
Band G3
Transcripts
ENSMUST00000016631 ENSMUSP00000016631
ENSMUST00000111623 ENSMUSP00000107250
ENSMUST00000154221 ENSMUSP00000122515
ENSMUST00000126774
ENSMUST00000123902
ENSMUST00000149203
ENSMUST00000133825
ENSMUST00000155415 ENSMUSP00000121270
ENSMUST00000136837 ENSMUSP00000114340
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.
Predicted by orthology
Total 13 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005575 cellular_component
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000110841
View Gene Order
ENSBTAG00000004283
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.103382 Mm.413381
RefSeq NM_001170433 NM_026221
OMIM
CCDS CCDS39715 CCDS51958
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca