Version 5.4
Homo sapiens Gene: BCL7B
Summary
InnateDB Gene IDBG-19936.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BCL7B
Gene Name B-cell CLL/lymphoma 7B
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000106635
Encoded Proteins
IDBP-19938
B-cell CLL/lymphoma 7B
IDBP-377554
B-cell CLL/lymphoma 7B
IDBP-377556
B-cell CLL/lymphoma 7B
IDBP-377558
B-cell CLL/lymphoma 7B
IDBP-377562
B-cell CLL/lymphoma 7B
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the BCL7 family including BCL7A, BCL7B and BCL7C proteins. This member is BCL7B, which contains a region that is highly similar to the N-terminal segment of BCL7A or BCL7C proteins. The BCL7A protein is encoded by the gene known to be directly involved in a three-way gene translocation in a Burkitt lymphoma cell line. This gene is located at a chromosomal region commonly deleted in Williams syndrome. This gene is highly conserved from C. elegans to human. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:73536356-73558002
Strand Reverse strand
Band q11.23
Transcripts
ENST00000223368 ENSP00000223368
ENST00000411832 ENSP00000393230
ENST00000454871 ENSP00000414473
ENST00000448175 ENSP00000414231
ENST00000455335 ENSP00000411073
ENST00000416906
ENST00000486818
ENST00000493671
ENST00000482231
ENST00000463858
ENST00000493679
ENST00000464288
ENST00000493592
ENST00000481667
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005575 cellular_component
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000029681
View Gene Order
ENSBTAG00000020544
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.647051
RefSeq NM_001197244 NM_001301061 NM_001707 XM_006716177
HUGO
OMIM
CCDS CCDS5550 CCDS56489 CCDS75613
HPRD 05786
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca