Version 5.4
Mus musculus Gene: Bcl7a
Summary
InnateDB Gene IDBG-199531.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Bcl7a
Gene Name B cell CLL/lymphoma 7A
Synonyms 4432415N06Rik; AI448316
Species Mus musculus
Ensembl Gene ENSMUSG00000029438
Encoded Proteins
IDBP-199533
B-cell CLL/lymphoma 7A
IDBP-400264
B-cell CLL/lymphoma 7A
IDBP-400263
B-cell CLL/lymphoma 7A
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000110987:
This gene is directly involved, with Myc and IgH, in a three-way gene translocation in a Burkitt lymphoma cell line. As a result of the gene translocation, the N-terminal region of the gene product is disrupted, which is thought to be related to the pathogenesis of a subset of high-grade B cell non-Hodgkin lymphoma. The N-terminal segment involved in the translocation includes the region that shares a strong sequence similarity with those of BCL7B and BCL7C. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:123343834-123374082
Strand Forward strand
Band F
Transcripts
ENSMUST00000031391 ENSMUSP00000031391
ENSMUST00000117971 ENSMUSP00000113264
ENSMUST00000120593 ENSMUSP00000112709
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005575 cellular_component
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000110987
View Gene Order
ENSBTAG00000032517
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_9
TNFalpha pathway
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL D3YU38
UniProt Splice Variant
Entrez Gene 77045
UniGene Mm.151960 Mm.397000 Mm.409987
RefSeq NM_029850
OMIM
CCDS CCDS19661
HPRD
IMGT
MGI ID MGI:1924295
MGI Symbol Bcl7a
EMBL AC113504
GenPept
RNA Seq Atlas 77045

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca