Version 5.4
Mus musculus Gene: Thrsp
Summary
InnateDB Gene IDBG-199716.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Thrsp
Gene Name thyroid hormone responsive
Synonyms S14
Species Mus musculus
Ensembl Gene ENSMUSG00000035686
Encoded Proteins
IDBP-199718
thyroid hormone responsive SPOT14 homolog (Rattus)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000151365:
The protein encoded by this gene is similar to the gene product of S14, a rat gene whose expression is limited to liver and adipose tissue and is controlled by nutritional and hormonal factors. This gene has been shown to be expressed in liver and adipocytes, particularly in lipomatous modules. It is also found to be expressed in lipogenic breast cancers, which suggests a role in controlling tumor lipid metabolism. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:97412938-97417730
Strand Reverse strand
Band E1
Transcripts
ENSMUST00000043077 ENSMUSP00000042988
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0042803 protein homodimerization activity
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006629 lipid metabolic process
GO:0010866 regulation of triglyceride biosynthetic process
GO:0046890 regulation of lipid biosynthetic process
Cellular Component
GO:0005634 nucleus
GO:0005829 cytosol
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000151365
View Gene Order
ENSBTAG00000011666
Not yet available
Cross-References
SwissProt Q62264
TrEMBL Q543J4 Q8BPB6
UniProt Splice Variant
Entrez Gene 21835
UniGene
RefSeq NM_009381
OMIM
CCDS CCDS21458
HPRD
IMGT
MGI ID MGI:109126
MGI Symbol Thrsp
EMBL AK050300 AK077300 BC009165 CH466531 X95279
GenPept AAH09165 BAC34175 BAC36737 CAA64600 EDL16296
RNA Seq Atlas 21835

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca