Version 5.4
Mus musculus Gene: Clip1
Summary
InnateDB Gene IDBG-199787.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Clip1
Gene Name CAP-GLY domain containing linker protein 1
Synonyms 1110007I12Rik; 4631429H07Rik; AV017631; C81039; CLIP-170; CLIP170; Clip50; CYLN1; mKIAA4046; restin; Rsn
Species Mus musculus
Ensembl Gene ENSMUSG00000049550
Encoded Proteins
IDBP-199789
CAP-GLY domain containing linker protein 1
IDBP-199791
CAP-GLY domain containing linker protein 1
IDBP-257855
CAP-GLY domain containing linker protein 1
IDBP-257857
CAP-GLY domain containing linker protein 1
IDBP-257859
CAP-GLY domain containing linker protein 1
IDBP-541415
CAP-GLY domain containing linker protein 1
IDBP-533677
CAP-GLY domain containing linker protein 1
IDBP-538042
CAP-GLY domain containing linker protein 1
IDBP-538819
CAP-GLY domain containing linker protein 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000130779:
The protein encoded by this gene links endocytic vesicles to microtubules. This gene is highly expressed in Reed-Sternberg cells of Hodgkin disease. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:123577795-123684618
Strand Reverse strand
Band F
Transcripts
ENSMUST00000031382 ENSMUSP00000031382
ENSMUST00000063905 ENSMUSP00000068241
ENSMUST00000111566 ENSMUSP00000107192
ENSMUST00000111564 ENSMUSP00000107190
ENSMUST00000111561 ENSMUSP00000107186
ENSMUST00000137363 ENSMUSP00000121425
ENSMUST00000125340
ENSMUST00000137602
ENSMUST00000154672 ENSMUSP00000122064
ENSMUST00000133545
ENSMUST00000154432
ENSMUST00000144121 ENSMUSP00000119641
ENSMUST00000149410 ENSMUSP00000115965
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 15 interaction(s) predicted by orthology.
Experimentally validated
Total 10 [view]
Protein-Protein 10 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 15 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0005515 protein binding
GO:0008017 microtubule binding
GO:0008270 zinc ion binding
GO:0015631 tubulin binding
GO:0051010 microtubule plus-end binding
Biological Process
GO:0001578 microtubule bundle formation
GO:0006810 transport
GO:0031116 positive regulation of microtubule polymerization
Cellular Component
GO:0001726 ruffle
GO:0005813 centrosome
GO:0005874 microtubule
GO:0005881 cytoplasmic microtubule
GO:0015630 microtubule cytoskeleton
GO:0030659 cytoplasmic vesicle membrane
GO:0035371 microtubule plus-end
GO:0044354 macropinosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000130779
View Gene Order
ENSBTAG00000016779
Not yet available
Pathways
NETPATH
REACTOME
REACT_249770
Cell Cycle, Mitotic pathway
REACT_207679
Separation of Sister Chromatids pathway
REACT_198961
Resolution of Sister Chromatid Cohesion pathway
REACT_188804
Cell Cycle pathway
REACT_241408
M Phase pathway
REACT_199403
Mitotic Metaphase and Anaphase pathway
REACT_256756
Mitotic Prometaphase pathway
REACT_202512
Mitotic Anaphase pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_150425
Resolution of Sister Chromatid Cohesion pathway
REACT_682
Mitotic Prometaphase pathway
REACT_150471
Separation of Sister Chromatids pathway
REACT_115566
Cell Cycle pathway
REACT_910
M Phase pathway
REACT_1275
Mitotic Anaphase pathway
REACT_152
Cell Cycle, Mitotic pathway
REACT_150314
Mitotic Metaphase and Anaphase pathway
KEGG
INOH
PID NCI
mtor_4pathway
mTOR signaling pathway
lis1pathway
Lissencephaly gene (LIS1) in neuronal migration and development
Cross-References
SwissProt
TrEMBL D3Z2Z1
UniProt Splice Variant
Entrez Gene 56430
UniGene Mm.241109
RefSeq XM_006530422 NM_001291229 NM_019765 XM_006530407 XM_006530408 XM_006530409 XM_006530410 XM_006530411 XM_006530412 XM_006530413 XM_006530414 XM_006530415 XM_006530416 XM_006530417 XM_006530418 XM_006530419 XM_006530423 XM_006530424 XM_006530425 XM_006530426
OMIM
CCDS CCDS19667 CCDS71663
HPRD
IMGT
MGI ID MGI:1928401
MGI Symbol Clip1
EMBL AC129569
GenPept
RNA Seq Atlas 56430

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca