Version 5.4
Mus musculus Gene: Fubp1
Summary
InnateDB Gene IDBG-199952.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Fubp1
Gene Name far upstream element (FUSE) binding protein 1
Synonyms 9530027K12Rik; D3Ertd330e; FBP; Fubp; Fubp4
Species Mus musculus
Ensembl Gene ENSMUSG00000028034
Encoded Proteins
IDBP-269424
far upstream element (FUSE) binding protein 1
IDBP-621761
far upstream element (FUSE) binding protein 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000162613:
This gene encodes a ssDNA binding protein that activates the far upstream element (FUSE) of c-myc and stimulates expression of c-myc in undifferentiated cells. Regulation of FUSE by FUBP occurs through single-strand binding of FUBP to the non-coding strand. This protein has been shown to function as an ATP-dependent DNA helicase. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:152210458-152236830
Strand Forward strand
Band H3
Transcripts
ENSMUST00000106121 ENSMUSP00000101727
ENSMUST00000166984 ENSMUSP00000130145
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 38 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 38 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001205 RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0010628 positive regulation of gene expression
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000162613
View Gene Order
ENSBTAG00000008926
Not yet available
Cross-References
SwissProt
TrEMBL Q3TUE1
UniProt Splice Variant
Entrez Gene 51886
UniGene Mm.278922 Mm.416679 Mm.419080 Mm.468325
RefSeq NM_057172 XM_006501666 XM_006501669 XM_006501673 XM_006501674
OMIM
CCDS CCDS38672
HPRD
IMGT
MGI ID MGI:1196294
MGI Symbol Fubp1
EMBL AC123075 AK160815
GenPept BAE36030
RNA Seq Atlas 51886

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca