Version 5.4
Mus musculus Gene: Doc2b
Summary
InnateDB Gene IDBG-200609.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Doc2b
Gene Name double C2, beta
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000020848
Encoded Proteins
IDBP-200611
double C2, beta
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog null:
There are at least two protein isoforms of the Double C2 protein, namely alpha (DOC2A) and beta (DOC2B), which contain two C2-like domains. DOC2A and DOC2B are encoded by different genes; these genes are at times confused with the unrelated DAB2 gene which was initially named DOC-2. DOC2B is expressed ubiquitously and is suggested to be involved in Ca(2+)-dependent intracellular vesicle trafficking in various types of cells. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:75768966-75796049
Strand Reverse strand
Band B5
Transcripts
ENSMUST00000021209 ENSMUSP00000021209
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005215 transporter activity
GO:0005515 protein binding
GO:0005544 calcium-dependent phospholipid binding
GO:0019905 syntaxin binding
Biological Process
GO:0008104 protein localization
GO:0031340 positive regulation of vesicle fusion
GO:0032024 positive regulation of insulin secretion
GO:0045956 positive regulation of calcium ion-dependent exocytosis
GO:0048791 calcium ion-dependent exocytosis of neurotransmitter
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0008021 synaptic vesicle
GO:0015630 microtubule cytoskeleton
GO:0031201 SNARE complex
Orthologs
Species
Homo sapiens
Gene ID
Gene Order
null
View Gene Order
Cross-References
SwissProt P70169
TrEMBL Q924P1
UniProt Splice Variant
Entrez Gene 13447
UniGene Mm.416045 Mm.487242 Mm.5137
RefSeq NM_007873
OMIM
CCDS CCDS25057
HPRD
IMGT
MGI ID MGI:1100497
MGI Symbol Doc2b
EMBL AF164955 AL669897 BC067030 CH466596 D85037
GenPept AAH67030 AAK73775 BAA12714 CAI26032 EDL12842
RNA Seq Atlas 13447

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca