Mus musculus Gene: Abcg5 | |||||||||||||||||||||
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Summary | |||||||||||||||||||||
InnateDB Gene | IDBG-200680.6 | ||||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||
Gene Symbol | Abcg5 | ||||||||||||||||||||
Gene Name | ATP-binding cassette, sub-family G (WHITE), member 5 | ||||||||||||||||||||
Synonyms | AW112016; cmp; sterolin-1; trac | ||||||||||||||||||||
Species | Mus musculus | ||||||||||||||||||||
Ensembl Gene | ENSMUSG00000040505 | ||||||||||||||||||||
Encoded Proteins |
ATP-binding cassette, sub-family G (WHITE), member 5
ATP-binding cassette, sub-family G (WHITE), member 5
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Protein Structure | |||||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||
Summary |
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. In humans, this protein functions as a half-transporter to limit intestinal absorption and promote biliary excretion of sterols; however, the function of the mouse gene has not been determined. Mutations in the human gene have been associated with sterol accumulation, atheroschlerosis, and sitosterolemia. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||||||||||||||||
Type | Protein coding | ||||||||||||||||||||
Genomic Location | Chromosome 17:84658234-84683011 | ||||||||||||||||||||
Strand | Reverse strand | ||||||||||||||||||||
Band | E4 | ||||||||||||||||||||
Transcripts |
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Interactions | |||||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||||
Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||||||||||||||
NETPATH | |||||||||||||||||||||
REACTOME |
Trafficking of dietary sterols pathway
Metabolism pathway
ABCA transporters in lipid homeostasis pathway
Metabolism of lipids and lipoproteins pathway
Lipid digestion, mobilization, and transport pathway
Transmembrane transport of small molecules pathway
ABC-family proteins mediated transport pathway
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KEGG |
ABC transporters pathway
Bile secretion pathway
Fat digestion and absorption pathway
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INOH | |||||||||||||||||||||
PID NCI | |||||||||||||||||||||
Pathway Predictions based on Human Orthology Data | |||||||||||||||||||||
NETPATH | |||||||||||||||||||||
REACTOME |
ABCA transporters in lipid homeostasis pathway
ABC-family proteins mediated transport pathway
Trafficking of dietary sterols pathway
Transmembrane transport of small molecules pathway
Metabolism of lipids and lipoproteins pathway
Metabolism pathway
Lipid digestion, mobilization, and transport pathway
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KEGG |
ABC transporters pathway
Fat digestion and absorption pathway
Bile secretion pathway
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INOH | |||||||||||||||||||||
PID NCI | |||||||||||||||||||||
Cross-References | |||||||||||||||||||||
SwissProt | |||||||||||||||||||||
TrEMBL | |||||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||
UniGene | Mm.289590 | ||||||||||||||||||||
RefSeq | NM_031884 | ||||||||||||||||||||
OMIM | |||||||||||||||||||||
CCDS | CCDS29001 | ||||||||||||||||||||
HPRD | |||||||||||||||||||||
IMGT | |||||||||||||||||||||
MGI ID | |||||||||||||||||||||
MGI Symbol | |||||||||||||||||||||
EMBL | |||||||||||||||||||||
GenPept | |||||||||||||||||||||
RNA Seq Atlas | |||||||||||||||||||||