Version 5.4
Mus musculus Gene: Slc3a1
Summary
InnateDB Gene IDBG-200904.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Slc3a1
Gene Name solute carrier family 3, member 1
Synonyms D2H; NBAT; NTAA; RBAT
Species Mus musculus
Ensembl Gene ENSMUSG00000024131
Encoded Proteins
IDBP-200906
solute carrier family 3, member 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000138079:
This gene encodes a type II membrane glycoprotein which is one of the components of the renal amino acid transporter which transports neutral and basic amino acids in the renal tubule and intestinal tract. Mutations and deletions in this gene are associated with cystinuria. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:85028347-85064243
Strand Forward strand
Band E4
Transcripts
ENSMUST00000024944 ENSMUSP00000024944
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0005515 protein binding
GO:0043169 cation binding
GO:0046982 protein heterodimerization activity
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0006865 amino acid transport
Cellular Component
GO:0005743 mitochondrial inner membrane
GO:0005774 vacuolar membrane
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0031526 brush border membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000138079
View Gene Order
ENSBTAG00000017421
Not yet available
Pathways
NETPATH
REACTOME
REACT_247550
SLC-mediated transmembrane transport pathway
REACT_251788
Transport of inorganic cations/anions and amino acids/oligopeptides pathway
REACT_253400
Transmembrane transport of small molecules pathway
REACT_230460
Amino acid transport across the plasma membrane pathway
KEGG
mmu04974
Protein digestion and absorption pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_13796
Amino acid transport across the plasma membrane pathway
REACT_19397
Transport of inorganic cations/anions and amino acids/oligopeptides pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_19118
SLC-mediated transmembrane transport pathway
KEGG
hsa04974
Protein digestion and absorption pathway
INOH
PID NCI
Cross-References
SwissProt Q91WV7
TrEMBL
UniProt Splice Variant
Entrez Gene 20532
UniGene Mm.227176
RefSeq NM_009205
OMIM
CCDS CCDS37711
HPRD
IMGT
MGI ID MGI:1195264
MGI Symbol Slc3a1
EMBL AC113476 AK052623 AK132275 BC013441 CH466537
GenPept AAH13441 BAC35066 BAE21075 EDL38594
RNA Seq Atlas 20532

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca